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WEHI Research Computing Platform

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Immunology Web Application

Introduction

When challenged with an infection, or cancer, our immune system needs to rapidly produce new immune cells to fight the attack. Once the pathogen is cleared, these cells need to die away. Immune cells have therefore evolved highly tuned strategies to determine when they should divide, how long they need to divide for and when they need to die. Our lab has developed a sophisticated mathematical model, called Cyton, that can extract the parameters underlying these fate decisions from experimental data.

The Cyton model is internationally recognised as a critical component in analysis and design of experiments of quantitative immune responses. To make Cyton accessible to the scientific community, we would like to provide a web application that researchers can access with their browsers from anywhere in the world. When complete, the project will be published as open source.

Duties while on placement

The Research Software Engineer Intern role will:

Skills and pre-requisites

The skills required for this project are expertise in python and experience developing web applications. Initial assessment of applicants will be based on a demonstration application and code repository for which the applicant has made a significant contribution.

Benefits for students

Other information

The web application is a reimplementation of this Python application https://github.com/evan-wehi/cyton-solver